ea0041ep629 | Endocrine tumours and neoplasia | ECE2016
Ademoglu Esra
, Candan Zehra
, Gorar Suheyla
, Niyazoglu Mutlu
, Carlioglu Ayse
, Yildiz Faruk
, Baydar Idris
, Sevimli Hakan
, Arslan Abdulmuttalib
Introduction: Acromegaly is a chronic disorder characterized by chronic growth hormone (GH) excess. In most of cases, GH hypersecretion is derived from somatotroph cell tumors. Survivin is a member of apoptosis protein family, which was recently showed to be expressed in different benign and malignant human tumors. A number of studies showed overexpression of survivin in pituitary adenomas. This study is intended to determine circulating levels of survivin in patients with acr...